Relative Biological Effectiveness (RBE) and its Relation with Dose Essay Example

Relative Biological Effectiveness (RBE) and its Relation with Dose Essay Example Relative Biological Effectiveness (RBE) and its Relation with Dose Paper Relative Biological Effectiveness (RBE) and its Relation with Dose Paper The article focuses mainly on the determination mechanism of relative biological effectiveness (RBE) of radiation as a medical technique. The dose effect is normally used in the determination of this effect; and the result show differences for live and dead cells. The presence of complex reactions also poses difficulty in arriving to the valid conclusions. Because of this, the dose effect relationship is eliminated and is replaced with dose-RBE relationship in order to prevent the limitations. The physical quantities are under consideration in the dose-RBE, since RBE becomes the ratio of doses of equal effect. It was identified further that the type of critical cell is important in establishing the RBE. There are some specific considerations which pertain to the effect of low-energy neutrons and high energy neutrons to the deactivation mechanism of electromagnetic radiation by electrons, either by 1-particle or 2-particle mechanisms. The doses of x-ray and ? -rays do not have the expected effect of producing primary lesions because it cannot produce neutrons with energies up to 14MeV, but produces two electrons in radiation. The neutron radiation even at low doses can execute lesion production, but then it was still discovered that the two-electron system of x-ray can produce lesions. The study proceeds with the lesion effects and extent, using the specific energy value, z, produced in the site of radiation by single particle track or the method of superimposition of several tracks. The findings say that there is direct proportionality between effect probability and the square of the specific energy in a region above 1 Â µm. It is noted that there are arguments presented indicative of the similar dependence on z of the x-rays and neutrons of intermediate energy composition. It is determined that probability effects particles exceeding 100 keV/Â µm (high energy neutrons) have a lower proportionality to z2.